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Table 1 Sputum MMP-9 concentrations and activity in sputum fluid from patients with COPD and healthy controls [Median (IQR)]

From: Sputum matrix metalloproteinase-9 is associated with the degree of emphysema on computed tomography in COPD

   MMP-9 (ng/mL) MMP-9 activity (ng/mL)
Healthy Control All 49.80 (26.35, 136.50) 18.90 (12.50, 38.35)
Never smoker 34.05 (24.45, 131.00) 16.60 (12.50, 28.42)
Smoker 69.00 (38.65, 184.00) 18.90 (13.40, 46.45)
p value 1 p = 0.161 p = 0.285
COPD All 137.50 (45.52, 362.95) 26.65 (12.50, 51.85)
Ex- smoker 214.75 (101.12, 445.05) 42.10 (26.02, 116.10)
Smoker 56.10 (28.90, 190.70) 12.50 (12.50, 32.52)
p value 2 p = 0.002 p < 0.001
p value 3 p = 0.007 p = 0.187
p value 4 p = 0.343 p = 0.787
p value 5 p < 0.001 p < 0.001
p value 6 p = 0.617 p = 0.086
  1. 1 Healthy smokers vs. healthy never smoker; 2 COPD smokers vs COPD ex-smokers;
  2. 3 All COPD subjects vs. healthy never smokers; 4 All COPD subjects vs. healthy smokers;
  3. 5 COPD ex-smokers vs. healthy never smokers; 6 COPD smokers vs. healthy smokers.