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Table 1 Sputum MMP-9 concentrations and activity in sputum fluid from patients with COPD and healthy controls [Median (IQR)]

From: Sputum matrix metalloproteinase-9 is associated with the degree of emphysema on computed tomography in COPD

  

MMP-9 (ng/mL)

MMP-9 activity (ng/mL)

Healthy Control

All

49.80 (26.35, 136.50)

18.90 (12.50, 38.35)

Never smoker

34.05 (24.45, 131.00)

16.60 (12.50, 28.42)

Smoker

69.00 (38.65, 184.00)

18.90 (13.40, 46.45)

p value 1

p = 0.161

p = 0.285

COPD

All

137.50 (45.52, 362.95)

26.65 (12.50, 51.85)

Ex- smoker

214.75 (101.12, 445.05)

42.10 (26.02, 116.10)

Smoker

56.10 (28.90, 190.70)

12.50 (12.50, 32.52)

p value 2

p = 0.002

p < 0.001

p value 3

p = 0.007

p = 0.187

p value 4

p = 0.343

p = 0.787

p value 5

p < 0.001

p < 0.001

p value 6

p = 0.617

p = 0.086

  1. 1 Healthy smokers vs. healthy never smoker; 2 COPD smokers vs COPD ex-smokers;
  2. 3 All COPD subjects vs. healthy never smokers; 4 All COPD subjects vs. healthy smokers;
  3. 5 COPD ex-smokers vs. healthy never smokers; 6 COPD smokers vs. healthy smokers.