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Table 2 Some enriched pathways and biological processes among the dysregulated genes in Caucasian American patients

From: MicroRNAs implicated in dysregulation of gene expression following human lung transplantation

Gene group Pathway category Count P Fold enrichment FDR
all GO:0009617 ~ response to bacterium 16 1.09E-06 4.74 0.002
GO:0006955 ~ immune response 33 1.39E-06 2.56 0.001
REACT_604:Hemostasis 20 3.31E-05 2.81 0.001
GO:0009611 ~ response to wounding 26 8.98E-05 2.37 0.054
GO:0006952 ~ defense response 26 1.40E-04 2.31 0.063
down-regulated REACT_604:Hemostasis 18 4.50E-05 2.96 0.002
GO:0050817 ~ coagulation 10 6.18E-05 5.61 0.083
GO:0007596 ~ blood coagulation 10 6.18E-05 5.61 0.083
GO:0007599 ~ hemostasis 10 7.70E-05 5.46 0.052
up-regulated GO:0009617 ~ response to bacterium 10 4.11E-08 13.25 0.000
GO:0006955 ~ immune response 13 1.77E-05 4.52 0.004
GO:0006952 ~ defense response 12 2.76E-05 4.76 0.005
GO:0007610 ~ behavior 10 8.23E-05 5.30 0.009
GO:0010033 ~ response to organic substance 12 5.42E-04 3.41 0.040
GO:0009611 ~ response to wounding 10 5.80E-04 4.08 0.040
  1. GO Gene Ontology biological process, REACT Reactome pathway, FDR false discovery rate.