Table 2 Some enriched pathways and biological processes among the dysregulated genes in Caucasian American patients
From: MicroRNAs implicated in dysregulation of gene expression following human lung transplantation
Gene group | Pathway category | Count | P | Fold enrichment | FDR |
|---|---|---|---|---|---|
all | GO:0009617 ~ response to bacterium | 16 | 1.09E-06 | 4.74 | 0.002 |
GO:0006955 ~ immune response | 33 | 1.39E-06 | 2.56 | 0.001 | |
REACT_604:Hemostasis | 20 | 3.31E-05 | 2.81 | 0.001 | |
GO:0009611 ~ response to wounding | 26 | 8.98E-05 | 2.37 | 0.054 | |
GO:0006952 ~ defense response | 26 | 1.40E-04 | 2.31 | 0.063 | |
down-regulated | REACT_604:Hemostasis | 18 | 4.50E-05 | 2.96 | 0.002 |
GO:0050817 ~ coagulation | 10 | 6.18E-05 | 5.61 | 0.083 | |
GO:0007596 ~ blood coagulation | 10 | 6.18E-05 | 5.61 | 0.083 | |
GO:0007599 ~ hemostasis | 10 | 7.70E-05 | 5.46 | 0.052 | |
up-regulated | GO:0009617 ~ response to bacterium | 10 | 4.11E-08 | 13.25 | 0.000 |
GO:0006955 ~ immune response | 13 | 1.77E-05 | 4.52 | 0.004 | |
GO:0006952 ~ defense response | 12 | 2.76E-05 | 4.76 | 0.005 | |
GO:0007610 ~ behavior | 10 | 8.23E-05 | 5.30 | 0.009 | |
GO:0010033 ~ response to organic substance | 12 | 5.42E-04 | 3.41 | 0.040 | |
GO:0009611 ~ response to wounding | 10 | 5.80E-04 | 4.08 | 0.040 |