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Table 1 Studies of the lung microbiome in COPD

From: Bacteria in COPD; their potential role and treatment

Study Subjects (n) Sample Key findings
Hilty et al. 2010 [21] 8 Control BAL/Brush Pathogenic bacteria, e.g. H. influenzae in asthma and COPD subjects
11 Asthma
5 COPD
Charlson et al. 2010 [22] 29 Smoker Pharynx Different regions of pharynx have different microbial communities which are changed by smoking
33 Non-smoker
Erb-Downward et al. 2011 [23] 9 Control/ BAL Core pulmonary microbiota in BAL & lung tissue
5 COPD
6 severe COPD
Sze et al. 2012 [24] 8 Control Lung tissue Differences in bacterial communities in the same lung
8 COPD
8 severe COPD
8 Cystic fibrosis
Pragmann et al. 2012 [25] 10 Control BAL Detectable bacterial communities in lung tissue that changes in severe COPD
22 COPD
Morris et al. 2013 [15] 32 Smoker Oral wash Mouth communities different in smoker
30 Non-smoker