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Figure 1 | Translational Respiratory Medicine

Figure 1

From: Pulmonary vascular remodeling and right heart failure in pulmonary hypertension: future role of positron emission tomography in decoding the enigma

Figure 1

11 C-Acetate wash-out scans of the lungs of a control subject (upper panel) and a patient with pulmonary arterial hypertension (PAH, lower panel. There is a suggestion of a decreased acetate wash-out in the PAH patient, which is compatible with a lower oxygen uptake. This would comply with a metabolic shift in the lung characterized by a decreased glucose oxidation and an increased reliance on anaerobic metabolism. These findings need to be confirmed in a larger group of patients and controls.

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