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Table 1 High concentration versus titrated oxygen therapy in the pre-hospital setting in patients with confirmed COPD

From: The effect of high concentration oxygen therapy on PaCO2 in acute and chronic respiratory disorders

  High concentration Titrated Relative risk (95% CI) Difference P Value
Mortality 9% 2% 0.22 (0.5 to 0.91)   0.04
Ventilation 14% 10% 0.67 (0.29 to 1.54)   0.34
Arterial blood gases†      
 Mean (SD) pH 7.29 (0.15) 7.41 (0.09)   0.12 0.01
 Mean (SD) PaCO2 (mmHg) 76.5 (50.2) 42.9 (14.2)   −33.6 0.02
 Mean (SD) PaO2 (mmHg) 98.4 (46.1) 81.5 (30.9)   −16.9 0.46
  1. † Treatment per protocol analysis.
  2. Reproduced with modification from reference [3].