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Table 2 Pulmonary symptoms and results of questionnaires, laboratory tests, and spirometry of patients with and without COPD based on spirometry

From: Serial pulmonary function tests to diagnose COPD in chronic heart failure

 

All (n = 187)

No COPD (n = 127)

COPD (n = 60)

P-value

Symptoms, n (%)

    

Cough

67 (36)

38 (30)

29 (48)

0.014

Sputum

43 (23)

26 (20)

17 (28)

0.233

Dyspnoea

153 (82)

101 (80)

52 (87)

0.237

ABHR

55 (29)

29 (23)

26 (43)

0.004

Questionnaires

    

MLHFQ

20 ± 17

19 ± 17

21 ± 18

0.568

MRC

1.5 ± 1.3

1.4 ± 1.3

1.7 ± 1.4

0.149

Borg

0.9 ± 1.2

0.8 ± 1.2

1.1 ± 1.3

0.036

Laboratory data

    

NT-pro-BNP1, pmol/L

201 ± 289

184 ± 273

236 ± 321

0.290

NT-pro-BNP2, pmol/L

198 ± 308

179 ± 289

239 ± 345

0.250

Spirometry

    

FEV1, L

2.5 ± 0.8

2.7 ± 0.8

2.1 ± 0.7

0.000

FEV1, % predicted

88 ± 21

96 ± 15

72 ± 22

0.000

FVC, L

3.7 ± 1.0

3.7 ± 1.0

3.8 ± 1.0

0.699

FVC, % predicted

102 ± 19

102 ± 17

101 ± 23

0.602

FEV1/FVC, %

68 ± 11

74 ± 5

55 ± 10

0.000

  1. Data are presented as mean ± SD. Only pre-bronchodilator lung function test results are presented to make comparison between groups possible. Laboratory data 1 and 2 refer to first (at baseline) and second (one month later) blood samples, respectively.
  2. Abbreviations: ABHR aspecific bronchial hyperreactivity, COPD chronic obstructive pulmonary disease, FEV 1 /FVC ratio of forced expiratory volume in one second to forced vital capacity, MLHFQ Minnesota Living with Heart Failure Questionnaire, MRC modified Medical Research Council dyspnoea scale, NT-pro-BNP N-terminal pro-B natriuretic peptide.