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Table 2 Pulmonary symptoms and results of questionnaires, laboratory tests, and spirometry of patients with and without COPD based on spirometry

From: Serial pulmonary function tests to diagnose COPD in chronic heart failure

  All (n = 187) No COPD (n = 127) COPD (n = 60) P-value
Symptoms, n (%)     
Cough 67 (36) 38 (30) 29 (48) 0.014
Sputum 43 (23) 26 (20) 17 (28) 0.233
Dyspnoea 153 (82) 101 (80) 52 (87) 0.237
ABHR 55 (29) 29 (23) 26 (43) 0.004
Questionnaires     
MLHFQ 20 ± 17 19 ± 17 21 ± 18 0.568
MRC 1.5 ± 1.3 1.4 ± 1.3 1.7 ± 1.4 0.149
Borg 0.9 ± 1.2 0.8 ± 1.2 1.1 ± 1.3 0.036
Laboratory data     
NT-pro-BNP1, pmol/L 201 ± 289 184 ± 273 236 ± 321 0.290
NT-pro-BNP2, pmol/L 198 ± 308 179 ± 289 239 ± 345 0.250
Spirometry     
FEV1, L 2.5 ± 0.8 2.7 ± 0.8 2.1 ± 0.7 0.000
FEV1, % predicted 88 ± 21 96 ± 15 72 ± 22 0.000
FVC, L 3.7 ± 1.0 3.7 ± 1.0 3.8 ± 1.0 0.699
FVC, % predicted 102 ± 19 102 ± 17 101 ± 23 0.602
FEV1/FVC, % 68 ± 11 74 ± 5 55 ± 10 0.000
  1. Data are presented as mean ± SD. Only pre-bronchodilator lung function test results are presented to make comparison between groups possible. Laboratory data 1 and 2 refer to first (at baseline) and second (one month later) blood samples, respectively.
  2. Abbreviations: ABHR aspecific bronchial hyperreactivity, COPD chronic obstructive pulmonary disease, FEV 1 /FVC ratio of forced expiratory volume in one second to forced vital capacity, MLHFQ Minnesota Living with Heart Failure Questionnaire, MRC modified Medical Research Council dyspnoea scale, NT-pro-BNP N-terminal pro-B natriuretic peptide.