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Translational Respiratory Medicine
Figure 1 | Translational Respiratory Medicine

Figure 1

From: A half doubling dose change in bronchial hyperresponsiveness in a population represents an important difference

Figure 1

Frequency distribution of asthma severity as measured by the cumulative dose of histamine which causes a 20% fall in FEV 1 . The small change in bronchial hyperresponsiveness (↔) in the population results in a small increase in the proportion of patients with moderate asthma but a substantial increase in the proportion with severe asthma. [Reproduced from Reference [12].

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